A Botox sulfate-free conditioner benefits like deeper conditioning, hair smoothing, and shine enhancement without the harshness of sulfates. It can also help maintain the longevity of a hair Botox treatment by avoiding ingredients that can strip the hair of its natural oils. Sulfates are common cleansing agents that, while useful, tend to dry, stress and damage. Sulfate-free formulas are gentler and better suited for hair that has been treated with Botox. They help maintain the smooth, hydrated results. Deep Conditioning.